Kits for Endogenous GAG NRE Biomarkers for IDUA and/or I2S Deficiency are Here!
GelbChem is introducing LDT kits to streamline your Endogenous GAG NRE Biomarker analysis! The kits include:
Pre-portioned derivatization reagent;
q-NMR certified internal standard; and,
QC DBS for IDUA and/or I2S Deficiency biomarkers.
Publications from Professor Gelb's laboratory have indicated that the Endogenous GAG NRE Biomarkers are preferred for second tier screening of MPS-I and MPS-II (see References, below).
Check out the new Biomarker Kits and other Biomarker Products by clicking the button below.
The components of the biomarker kits are also available separately.
References:
Herbst, Z.M., Urdaneta, L., Klein, T., Fuller, M. and Gelb, M.H., 2020. Evaluation of multiple methods for quantification of glycosaminoglycan biomarkers in newborn dried blood spots from patients with severe and attenuated mucopolysaccharidosis-I. International journal of neonatal screening, 6(3), p.69.
Herbst, Z.M., Urdaneta, L., Klein, T., Burton, B.K., Basheeruddin, K., Liao, H.C., Fuller, M. and Gelb, M.H., 2022. Evaluation of two methods for quantification of glycosaminoglycan biomarkers in newborn dried blood spots from patients with severe and attenuated mucopolysaccharidosis Type II. International Journal of Neonatal Screening, 8(1), p.9.