top of page

Endogenous Glycosaminoglycan (GAG) Disaccharide, "UA-HNAc(1S)-Late" prepared with blood from a healthy adult. Product consists of one QC High DBS card prepared with blood from a healthy adult spiked with the Endogenous Disaccharide, "UA-HNAc(1S)-Late." One control DBS card prepared with unspiked blood is also provided. Each DBS card contains ten DBS. At least six 3 mm punches can be taken from each DBS.


*The Endogenous GAG Disaccharide, "UA-HNAc(1S)-Late," was described by Herbst et. al. as being elevated in 18 MPS-II Newborn DBS (I2S deficiency) when compared to a reference range of healthy newborns and newborns with I2S Pseudodeficiencies.


Internal Standard sold separately (product BM14A).

Endogenous GAG NRE Biomarker "UA-HNAc(1S)-Late" QC DBS

  • Herbst, Z.M., Urdaneta, L., Klein, T., Burton, B.K., Basheeruddin, K., Liao, H., Fuller, M., Gelb, M.H., 2022. Evaluation of Two Methods for Quantification of Glycosaminoglycan Biomarkers in Newborn Dried Blood Spots from Patients with Severe and Attenuated Mucopolysaccharidosis Type II. International Journal of Neonatal Screening, 8(1), p.9.

bottom of page