Kit for the LC-MS/MS analysis of the Endogenous GAG NRE Biomarker: UA-HNAc(1S)-Early. This GAG NRE has been cited in literature (Herbst et. al. 2020 ) as useful for second tier screening of MPS-I*.

The Kit includes the following QCs and Reagents for 3,000 Assays:
1 Vial of Internal Standard for 3,000 Assays (product BM14A);
75 Vials of Derivatization Reagent for 50 Assays;
1 QC "Negative" DBS Card (10 Spots, 60 punches);
1 QC "High" IDUA Deficiency DBS Card (10 Spots, 60 punches) (product QCEG-1).

Endogenous GAG NRE Biomarker Kit (IDUA Deficiency)

SKU: BMKEG-1

Herbst, Z.M., Urdaneta, L., Klein, T., Fuller, M. and Gelb, M.H., 2020. Evaluation of multiple methods for quantification of glycosaminoglycan biomarkers in newborn dried blood spots from patients with severe and attenuated mucopolysaccharidosis-I. International journal of neonatal screening, 6(3), p.69.

Endogenous GAG NRE Biomarker Kit (IDUA Deficiency)

LITERATURE