Deuterium labeled N-Hexadecanoyl-sulfatide (d5-labeled), biomarker internal standard for deficiency of Arylsulfatase A (ARSA).

Also known as d5-C16:0-Sulfatide.

The absolute amount of d5-C16:0-Sulfatide in the vial was determined using quantitative NMR to have the stated value on the vial. The vial may have additional components, but none are isobaric with d5-C16:0-Sulfatide, and these additional components have no effect on the ability to quantify the d5-C16:0-Sulfatide.

N-Hexadecanoyl-sulfatide (d5-labeled)

SKU: BM40A

N-Palmitoylsphingosinyl-β-galactoside-3-sulfate salt-d5

Catalog Number: BM40A

Chemical Formula: C40 H71 D5 N O11 S

Molar Mass (anion): 784.1

Approximate Amount per Assay: 3 pmol
Hong, Xinying, Jessica Daiker, Martin Sadilek, Nicole Ruiz-Schultz, Arun Babu Kumar, Stevie Norcross, Warunee Dansithong et al. "Toward newborn screening of metachromatic leukodystrophy: results from analysis of over 27,000 newborn dried blood spots." Genetics in Medicine (2020): 1-7.

Hong, X., Sadilek, M. and Gelb, M.H., 2020. A highly multiplexed biochemical assay for analytes in dried blood spots: application to newborn screening and diagnosis of lysosomal storage disorders and other inborn errors of metabolism. Genetics in Medicine, pp.1-7. DOI: 10.1038/s41436-020-0790-9

Spacil, Z., Kumar, A.B., Liao, H.C., Auray-Blais, C., Stark, S., Suhr, T.R., Scott, C.R., Turecek, F. and Gelb, M.H., 2016. Sulfatide analysis by mass spectrometry for screening of metachromatic leukodystrophy in dried blood and urine samples. Clinical chemistry, 62(1), pp.279-286.

N-Hexadecanoyl-sulfatide (d5-labeled)

PRODUCT INFO

LITERATURE AND PROTOCOL

MSDS